Translational Pharmacology Core
"Integrating Translational and Clinical Pharmacology Research within the Center of Excellence in Bioinformatics and Life Sciences"
Overview
The New York State Center of Excellence in Bioinformatics and Life Sciences (COE) has established a Translational Pharmacology Core (TPC) within the developing research infrastructure. The goals of the TPC core will be:
- To foster innovative translational pharmacology research in the areas of drug development, applied translational pharmacology, clinical pharmacology and pharmacogenomics and proteomics with an emphasis in oncology, neurology, infectious diseases and inflammation and cardiovascular disease.
- To facilitate collaboration among COE investigators with common areas of research interest and foster an interdisciplinary, interactive environment that stimulates grant submission and commercialization of drugs, drug delivery systems and diagnostics.
- To establish an integrated program that utilizes novel strategies for transitioning from pre-clinical drug development to a clinical research environment to optimize the approval process and provide a forum for exchange for research ideas through an interdisciplinary seminar program with presentations by national and international visiting scholars.
Description of the Translational Pharmacology Core (TPC)
1. The TPC provides a novel research program that will interface with multiple stages of drug development including drug discovery, pre-clinical evaluation, Phase I, II and III of the required FDA approval process as well as a developing network for conducting Phase IV (post-approval) research.
2. The TPC will foster the interaction of basic and clinical scientists who are focused on drug development and translational pharmacology.
3. The TPC will utilize in vitro experimental therapeutics models that will facilitate integrated pre-clinical approaches to pharmacokinetic, pharmacodynamic and pharmacogenetic investigations accompanied by in silico modeling techniques.
4. The TPC will facilitate novel approaches to examine clinical challenges within a interdisciplinary laboratory environment.
5. The COE TPC facilities will provide an efficient system with a quality assurance program to sustain standard operating procedures that are recognized as industry standards and an essential component for the pharmaceutical industry to recognize the COE as a primary site for drug development research.
6. Data management and data analysis units within the COE will be linked with clinical facilities through the UB Clinical and Translational Research Center, the Center for Computational Research (CCR) and National Center for Ontological Research.
The development of the TPC within the COE research infrastructure will accelerate the ability of the COE to develop pre-clinical, translational and clinical research programs for new therapeutics and devices. In addition corporate partners will be seeking to join the COE collaboration and this will foster the goal of commercialization and regional economic development.
News
Invitrogen Foundation Supports UB's Life Sciences Initiatives in Buffalo
11/07/2008 - BUFFALO, N.Y. -- "The Invitrogen Foundation headquartered in Carlsbad, Calif., has given the University at Buffalo $50,000 to support marketing and outreach efforts for UB's iSci: Career Pathways in the Life Sciences program..." [Read On...]
CoE Researchers Apply Systems Biology and Glycomics to Study Human Inflammatory Diseases
10/28/2008 - BUFFALO, N.Y. -- "It's an extremely valuable way to apply engineering principles to biology, it's critical to merge both approaches..." [Read On...]
Initiative to Develop Groundbreaking Medical Devices, Boost Industry
09/17/2008 - BUFFALO, N. Y. -- "Launch made possible by $3 million Oishei Foundation grant...UB is establishing a Dept. of Biomedical Engineering with a focus on developing groundbreaking medical devices and therapies to address society's most pressing health problems..." [Read On...]
Visit the News Archive
Events
November 20 - Life Sciences Commercialization Series
"CTG in the Center of Excellence: What this Collaboration is All About!" presented by Michael Colson, Sr. VP of Solutions Development. To learn more, click here.
November 20 - Biotechnology and Entrepreneurship Seminar Series
"Biotech Business Models for Sustained Survival and Success: Why do so Few Biotech Companies Survive and Succeed?" presented via live interactive video conference by Daniel P. vanPlew, Sr. VP and General Manager, Regeneron Pharmaceuticals Inc. To learn more, click here.
FREE BOOK RAFFLE FOLLOWING EVENT!
November 25 - WNY Career Fair
Interested in Advanced Manufacturing and Life Sciences careers? Join over 50 participating businesses and educational organizations to help make your career goal a reality. To learn more, click here.
To view the complete list of events and event details, please visit our Events page
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